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Publications

Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses.

Wang M, Lee-Kim VS, Atri DS, et al. Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses. Circ Genom Precis Med. 2021;14(5):e003399. doi:10.1161/CIRCGEN.121.003399

A field guide to cultivating computational biology.

Way GP, Greene CS, Carninci P, et al. A field guide to cultivating computational biology. PLoS Biol. 2021;19(10):e3001419. doi:10.1371/journal.pbio.3001419

Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer.

Coates JT, Sun S, Leshchiner I, et al. Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer. Cancer Discov. 2021;11(10):2436-2445. doi:10.1158/2159-8290.CD-21-0702

Biologically informed deep neural network for prostate cancer discovery.

Elmarakeby HA, Hwang J, Arafeh R, et al. Biologically informed deep neural network for prostate cancer discovery. Nature. 2021;598(7880):348-352. doi:10.1038/s41586-021-03922-4

Duplex-Repair enables highly accurate sequencing, despite DNA damage.

Xiong K, Shea D, Rhoades J, et al. Duplex-Repair enables highly accurate sequencing, despite DNA damage. Nucleic Acids Res. 2021. doi:10.1093/nar/gkab855

Molecular Alterations in Pediatric Low-Grade Gliomas That Led to Death.

Ahrendsen JT, Sinai C, Meredith DM, et al. Molecular Alterations in Pediatric Low-Grade Gliomas That Led to Death. J Neuropathol Exp Neurol. 2021. doi:10.1093/jnen/nlab097

Automating UbiFast for High-throughput and Multiplexed Ubiquitin Enrichment.

Rivera KD, Olive ME, Bergstrom EJ, et al. Automating UbiFast for High-throughput and Multiplexed Ubiquitin Enrichment. Mol Cell Proteomics. 2021:100154. doi:10.1016/j.mcpro.2021.100154

The influence of the gut microbiome on BCG-induced trained immunity.

Stražar M, Mourits VP, Koeken VACM, et al. The influence of the gut microbiome on BCG-induced trained immunity. Genome Biol. 2021;22(1):275. doi:10.1186/s13059-021-02482-0

TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response.

Zeng Z, Wong CJ, Yang L, et al. TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response. Nucleic Acids Res. 2021. doi:10.1093/nar/gkab804

Proteogenomic characterization of pancreatic ductal adenocarcinoma.

Cao L, Huang C, Zhou DC, et al. Proteogenomic characterization of pancreatic ductal adenocarcinoma. Cell. 2021;184(19):5031-5052.e26. doi:10.1016/j.cell.2021.08.023