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Publications

Novel Cannabinoid Receptor 2 (CB2) Low Lipophilicity Agonists Produce Distinct cAMP and Arrestin Signalling Kinetics without Bias.

Sharma R, Singh S, Whiting ZM, Molitor M, Vernall AJ, Grimsey NL. Novel Cannabinoid Receptor 2 (CB2) Low Lipophilicity Agonists Produce Distinct cAMP and Arrestin Signalling Kinetics without Bias. International journal of molecular sciences. 2023;24(7). doi:10.3390/ijms24076406

SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers.

Shi L, Shen W, Davis MI, et al. SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer. 2023;4(3):365-381. doi:10.1038/s43018-023-00523-0

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.

Shrine N, Izquierdo AG, Chen J, et al. Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nature genetics. 2023;55(3):410-422. doi:10.1038/s41588-023-01314-0

Genomes of four Streptomyces strains reveal insights into putative new species and pathogenicity of scab-causing organisms.

Henao L, Zade RSH, Restrepo S, Husserl J, Abeel T. Genomes of four Streptomyces strains reveal insights into putative new species and pathogenicity of scab-causing organisms. BMC genomics. 2023;24(1):143. doi:10.1186/s12864-023-09190-y

Diagnostic TR-FRET assays for detection of antibodies in patient samples.

Yue H, Nowak RP, Overwijn D, et al. Diagnostic TR-FRET assays for detection of antibodies in patient samples. Cell reports methods. 2023;3(3):100421. doi:10.1016/j.crmeth.2023.100421

Impaired adipocyte SLC7A10 promotes lipid storage in association with insulin resistance and altered BCAA metabolism.

Jersin RÅ, Tallapragada DSP, Skartveit L, et al. Impaired adipocyte SLC7A10 promotes lipid storage in association with insulin resistance and altered BCAA metabolism. The Journal of clinical endocrinology and metabolism. 2023. doi:10.1210/clinem/dgad148

A self-propagating, barcoded transposon system for the dynamic rewiring of genomic networks.

English MA, Alcantar MA, Collins JJ. A self-propagating, barcoded transposon system for the dynamic rewiring of genomic networks. Molecular systems biology. 2023:e11398. doi:10.15252/msb.202211398

A Mouse Model of Atrial Fibrillation in Sepsis.

Bapat A, Schloss MJ, Yamazoe M, et al. A Mouse Model of Atrial Fibrillation in Sepsis. Circulation. 2023;147(13):1047-1049. doi:10.1161/CIRCULATIONAHA.122.060317

Ancient mitogenomes from the Southern Pampas of Argentina reflect local differentiation and limited extra-regional linkages after rapid initial colonization.

Motti JMB, Pauro M, Scabuzzo C, et al. Ancient mitogenomes from the Southern Pampas of Argentina reflect local differentiation and limited extra-regional linkages after rapid initial colonization. American journal of biological anthropology. 2023. doi:10.1002/ajpa.24727

Single-cell atlas of the liver myeloid compartment before and after cure of chronic viral hepatitis.

Cui A, Li B, Wallace MS, et al. Single-cell atlas of the liver myeloid compartment before and after cure of chronic viral hepatitis. Journal of hepatology. 2023. doi:10.1016/j.jhep.2023.02.040