Publications

Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in EGFR-Mutant Lung Adenocarcinomas.

Elkrief A, Makhnin A, Moses KA, et al. Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in EGFR-Mutant Lung Adenocarcinomas. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023;29(8):1423-1428. doi:10.1158/1078-0432.CCR-22-3484

High-depth sequencing characterization of viral dynamics across tissues in fatal COVID-19 reveals compartmentalized infection.

Normandin E, Rudy M, Barkas N, et al. High-depth sequencing characterization of viral dynamics across tissues in fatal COVID-19 reveals compartmentalized infection. Nature communications. 2023;14(1):574. doi:10.1038/s41467-022-34256-y

Building a knowledge graph to enable precision medicine.

Chandak P, Huang K, Zitnik M. Building a knowledge graph to enable precision medicine. Scientific data. 2023;10(1):67. doi:10.1038/s41597-023-01960-3

Mapping thalamic innervation to individual L2/3 pyramidal neurons and modeling their 'readout' of visual input.

Balcioglu A, Gillani R, Doron M, et al. Mapping thalamic innervation to individual L2/3 pyramidal neurons and modeling their ’readout’ of visual input. Nature neuroscience. 2023;26(3):470-480. doi:10.1038/s41593-022-01253-9

LoFTK: a framework for fully automated calculation of predicted Loss-of-Function variants and genes.

Alasiri A, Karczewski KJ, Cole B, et al. LoFTK: a framework for fully automated calculation of predicted Loss-of-Function variants and genes. BioData mining. 2023;16(1):3. doi:10.1186/s13040-023-00321-5

Plasma protein and venous thromboembolism: prospective cohort and mendelian randomisation analyses.

Yuan S, Titova OE, Zhang K, et al. Plasma protein and venous thromboembolism: prospective cohort and mendelian randomisation analyses. British journal of haematology. 2023. doi:10.1111/bjh.18679

Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A.

Gonzalez-Menendez P, Phadke I, Olive ME, et al. Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A. Blood. 2023. doi:10.1182/blood.2022017584

Exploiting somatic mutations to decipher human blood production: a natural lineage-tracing strategy.

Bloom M, Malouf C, Rodriguez-Fraticelli A, Wilkinson AC, Sankaran VG, Cvejic A. Exploiting somatic mutations to decipher human blood production: a natural lineage-tracing strategy. Experimental hematology. 2023;121:2-5. doi:10.1016/j.exphem.2023.01.005

Moving away from one disease at a time: Screening, trial design, and regulatory implications of novel platform technologies.

Lekstrom-Himes J, Brooks PJ, Koeberl DD, et al. Moving away from one disease at a time: Screening, trial design, and regulatory implications of novel platform technologies. American journal of medical genetics. Part C, Seminars in medical genetics. 2023;193(1):30-43. doi:10.1002/ajmg.c.32031

Genome-wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome.

Tsetsos F, Topaloudi A, Jain P, et al. Genome-wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome. Biological psychiatry. 2023. doi:10.1016/j.biopsych.2023.01.023

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Publications

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