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Publications

Selective modulation of a pan-essential protein as a therapeutic strategy in cancer.

Malone CF, Dharia NV, Kugener G, et al. Selective modulation of a pan-essential protein as a therapeutic strategy in cancer. Cancer Discov. 2021. doi:10.1158/2159-8290.CD-20-1213

Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells.

Tian C, Huang Y, Clauser KR, et al. Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells. Nat Commun. 2021;12(1):2328. doi:10.1038/s41467-021-22490-9

Predicting cell health phenotypes using image-based morphology profiling.

Way GP, Kost-Alimova M, Shibue T, et al. Predicting cell health phenotypes using image-based morphology profiling. Mol Biol Cell. 2021;32(9):995-1005. doi:10.1091/mbc.E20-12-0784

Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics.

Ma P, He LL, Pironti A, et al. Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics. Elife. 2021;10. doi:10.7554/eLife.67310

Compressed sensing for highly efficient imaging transcriptomics.

Cleary B, Simonton B, Bezney J, et al. Compressed sensing for highly efficient imaging transcriptomics. Nat Biotechnol. 2021. doi:10.1038/s41587-021-00883-x

Elevated rates of horizontal gene transfer in the industrialized human microbiome.

Groussin M, Poyet M, Sistiaga A, et al. Elevated rates of horizontal gene transfer in the industrialized human microbiome. Cell. 2021;184(8):2053-2067.e18. doi:10.1016/j.cell.2021.02.052

Splice it up: Atypical transcripts to boost leukemia immunotherapy.

Cieri N, Wu CJ. Splice it up: Atypical transcripts to boost leukemia immunotherapy. Immunity. 2021;54(4):608-610. doi:10.1016/j.immuni.2021.03.016

Genome-Wide Analysis of Experimentally Evolved Candida auris Reveals Multiple Novel Mechanisms of Multidrug Resistance.

Carolus H, Pierson S, Muñoz JF, et al. Genome-Wide Analysis of Experimentally Evolved Candida auris Reveals Multiple Novel Mechanisms of Multidrug Resistance. mBio. 2021;12(2). doi:10.1128/mBio.03333-20

Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias.

Raundhal M, Ghosh S, Myers SA, et al. Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias. Nat Immunol. 2021;22(4):520-529. doi:10.1038/s41590-021-00895-4

A first-generation pediatric cancer dependency map.

Dharia NV, Kugener G, Guenther LM, et al. A first-generation pediatric cancer dependency map. Nat Genet. 2021;53(4):529-538. doi:10.1038/s41588-021-00819-w