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Publications

Remodeling of colon plasma cell repertoire within ulcerative colitis patients.

Scheid JF, Eraslan B, Hudak A, et al. Remodeling of colon plasma cell repertoire within ulcerative colitis patients. The Journal of experimental medicine. 2023;220(4). doi:10.1084/jem.20220538

Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.

Côrte-Real BF, Hamad I, Hornero RA, et al. Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs. Cell metabolism. 2023;35(2):299-315.e8. doi:10.1016/j.cmet.2023.01.009

MUC1-C is a master regulator of MICA/B NKG2D ligand and exosome secretion in human cancer cells.

Morimoto Y, Yamashita N, Daimon T, et al. MUC1-C is a master regulator of MICA/B NKG2D ligand and exosome secretion in human cancer cells. Journal for immunotherapy of cancer. 2023;11(2). doi:10.1136/jitc-2022-006238

Polygenic architecture of rare coding variation across 394,783 exomes.

Weiner DJ, Nadig A, Jagadeesh KA, et al. Polygenic architecture of rare coding variation across 394,783 exomes. Nature. 2023;614(7948):492-499. doi:10.1038/s41586-022-05684-z

Ancestry: How researchers use it and what they mean by it.

Dauda B, Molina SJ, Allen DS, et al. Ancestry: How researchers use it and what they mean by it. Frontiers in genetics. 2023;14:1044555. doi:10.3389/fgene.2023.1044555

Genetic Risk Score Improves Risk Stratification for Anticoagulation-Related Intracerebral Hemorrhage.

Mayerhofer E, Parodi L, Prapiadou S, et al. Genetic Risk Score Improves Risk Stratification for Anticoagulation-Related Intracerebral Hemorrhage. Stroke. 2023;54(3):791-799. doi:10.1161/STROKEAHA.122.041764

Gut microbiome lipid metabolism and its impact on host physiology.

Brown EM, Clardy J, Xavier RJ. Gut microbiome lipid metabolism and its impact on host physiology. Cell host & microbe. 2023;31(2):173-186. doi:10.1016/j.chom.2023.01.009

Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways.

Pun M, Pratt D, Nano PR, et al. Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways. Acta neuropathologica communications. 2023;11(1):25. doi:10.1186/s40478-023-01514-z

Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery.

Ngan KCH, Hoenig SM, Kwok HS, et al. Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. eLife. 2023;12. doi:10.7554/eLife.80640

Regulatory dissection of the severe COVID-19 risk locus introgressed by Neanderthals.

Jagoda E, Marnetto D, Senevirathne G, et al. Regulatory dissection of the severe COVID-19 risk locus introgressed by Neanderthals. eLife. 2023;12. doi:10.7554/eLife.71235