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Publications

Application of an optimized annotation pipeline to the Cryptococcus deuterogattii genome reveals dynamic primary metabolic gene clusters and genomic impact of RNAi loss.

Ferrareze PAG, Maufrais C, Streit RSA, et al. Application of an optimized annotation pipeline to the Cryptococcus deuterogattii genome reveals dynamic primary metabolic gene clusters and genomic impact of RNAi loss. G3 (Bethesda). 2021;11(2). doi:10.1093/g3journal/jkaa070

Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans.

Beekman CN, Cuomo CA, Bennett RJ, Ene IV. Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans. G3 (Bethesda). 2021;11(2). doi:10.1093/g3journal/jkab001

Biomarkers to distinguish bacterial from viral pediatric clinical pneumonia in a malaria endemic setting.

Gillette MA, Mani DR, Uschnig C, et al. Biomarkers to distinguish bacterial from viral pediatric clinical pneumonia in a malaria endemic setting. Clin Infect Dis. 2021. doi:10.1093/cid/ciaa1843

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.

Bernasocchi T, Tekle GE, Bolis M, et al. Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer. Nat Commun. 2021;12(1):734. doi:10.1038/s41467-020-20820-x

Advances in the classification and treatment of pediatric brain tumors.

Fangusaro J, Bandopadhayay P. Advances in the classification and treatment of pediatric brain tumors. Curr Opin Pediatr. 2021;33(1):26-32. doi:10.1097/MOP.0000000000000975

Targeting oncoproteins with a positive selection assay for protein degraders.

Koduri V, Duplaquet L, Lampson BL, et al. Targeting oncoproteins with a positive selection assay for protein degraders. Sci Adv. 2021;7(6). doi:10.1126/sciadv.abd6263

A wealth of discovery built on the Human Genome Project - by the numbers.

Gates AJ, Gysi DM, Kellis M, Barabási AL. A wealth of discovery built on the Human Genome Project - by the numbers. Nature. 2021;590(7845):212-215. doi:10.1038/d41586-021-00314-6

Regulatory genomic circuitry of human disease loci by integrative epigenomics.

Boix CA, James BT, Park YP, Meuleman W, Kellis M. Regulatory genomic circuitry of human disease loci by integrative epigenomics. Nature. 2021;590(7845):300-307. doi:10.1038/s41586-020-03145-z

Noncanonical open reading frames encode functional proteins essential for cancer cell survival.

Prensner JR, Enache OM, Luria V, et al. Noncanonical open reading frames encode functional proteins essential for cancer cell survival. Nat Biotechnol. 2021. doi:10.1038/s41587-020-00806-2

Antigen identification for HLA class I- and HLA class II-restricted T cell receptors using cytokine-capturing antigen-presenting cells.

Lee MN, Meyerson M. Antigen identification for HLA class I- and HLA class II-restricted T cell receptors using cytokine-capturing antigen-presenting cells. Sci Immunol. 2021;6(55). doi:10.1126/sciimmunol.abf4001