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Publications

Metabo-Endotypes of Asthma Reveal Differences in Lung Function: Discovery and Validation in Two TOPMed Cohorts.

Kelly RS, Mendez KM, Huang M, et al. Metabo-Endotypes of Asthma Reveal Differences in Lung Function: Discovery and Validation in Two TOPMed Cohorts. American journal of respiratory and critical care medicine. 2022;205(3):288-299. doi:10.1164/rccm.202105-1268OC

Metabolomic Analysis of Coronary Heart Disease in an African American Cohort From the Jackson Heart Study.

Cruz DE, Tahir UA, Hu J, et al. Metabolomic Analysis of Coronary Heart Disease in an African American Cohort From the Jackson Heart Study. JAMA cardiology. 2022;7(2):184-194. doi:10.1001/jamacardio.2021.4925

Metabolomic Profiles Associated With Incident Ischemic Stroke.

Balasubramanian R, Hu J, Guasch-Ferre M, et al. Metabolomic Profiles Associated With Incident Ischemic Stroke. Neurology. 2022;98(5):e483-e492. doi:10.1212/WNL.0000000000013129

Plasma Metabolite Profiles of Red Meat, Poultry, and Fish Consumption, and Their Associations with Colorectal Cancer Risk.

Wang F, Chandler PD, Zeleznik OA, et al. Plasma Metabolite Profiles of Red Meat, Poultry, and Fish Consumption, and Their Associations with Colorectal Cancer Risk. Nutrients. 2022;14(5). doi:10.3390/nu14050978

Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic.

Chow YL, Singh S, Carpenter AE, Way GP. Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic. PLoS Comput Biol. 2022;18(2):e1009888. doi:10.1371/journal.pcbi.1009888

Patient contrastive learning: A performant, expressive, and practical approach to electrocardiogram modeling.

Diamant N, Reinertsen E, Song S, Aguirre AD, Stultz CM, Batra P. Patient contrastive learning: A performant, expressive, and practical approach to electrocardiogram modeling. PLoS Comput Biol. 2022;18(2):e1009862. doi:10.1371/journal.pcbi.1009862

A roadmap to increase diversity in genomic studies.

Fatumo S, Chikowore T, Choudhury A, Ayub M, Martin AR, Kuchenbaecker K. A roadmap to increase diversity in genomic studies. Nat Med. 2022;28(2):243-250. doi:10.1038/s41591-021-01672-4

Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer.

Ouspenskaia T, Law T, Clauser KR, et al. Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer. Nat Biotechnol. 2022;40(2):209-217. doi:10.1038/s41587-021-01021-3

An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML.

Lin S, Larrue C, Scheidegger NK, et al. An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML. Cancer Discov. 2022;12(2):432-449. doi:10.1158/2159-8290.CD-20-1851

Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom.

Nguyen LH, Joshi AD, Drew DA, et al. Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom. Nat Commun. 2022;13(1):636. doi:10.1038/s41467-022-28200-3