ӳ��ý

Publications

SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance.

Liu K, Kong L, Graham DB, Carey KL, Xavier RJ. SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance. Cell Rep. 2021;36(4):109434. doi:10.1016/j.celrep.2021.109434

SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization.

Dai C, Rennhack JP, Arnoff TE, et al. SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization. Cell Rep. 2021;36(4):109443. doi:10.1016/j.celrep.2021.109443

Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling.

Whiteaker JR, Sharma K, Hoffman MA, et al. Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling. Cell Rep Methods. 2021;1(3). doi:10.1016/j.crmeth.2021.100015

A phase II study of efficacy, toxicity, and the potential impact of genomic alterations on response to eribulin mesylate in combination with trastuzumab and pertuzumab in women with human epidermal growth factor receptor 2 (HER2)+ metastatic breast cancer

Balch SM, Vaz-Luis I, Li T, et al. A phase II study of efficacy, toxicity, and the potential impact of genomic alterations on response to eribulin mesylate in combination with trastuzumab and pertuzumab in women with human epidermal growth factor receptor 2 (HER2)+ metastatic breast cancer. Breast Cancer Res Treat. 2021. doi:10.1007/s10549-021-06329-x

Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs.

Weingarten-Gabbay S, Klaeger S, Sarkizova S, et al. Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs. Cell. 2021;184(15):3962-3980.e17. doi:10.1016/j.cell.2021.05.046

TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma.

Seong BKA, Dharia NV, Lin S, et al. TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma. Cancer Cell. 2021. doi:10.1016/j.ccell.2021.07.003

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.

Garvie CW, Wu X, Papanastasiou M, et al. Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase. Nat Commun. 2021;12(1):4375. doi:10.1038/s41467-021-24495-w

Multi-Center Immune Profiling Mass Cytometry Assay Harmonization.

Sahaf B, Pichavant M, Lee BH, et al. Multi-Center Immune Profiling Mass Cytometry Assay Harmonization. Clin Cancer Res. 2021. doi:10.1158/1078-0432.CCR-21-2052

Cross-sectional assessment of SARS-CoV-2 viral load by symptom status in Massachusetts congregate living facilities.

Lennon NJ, Bhattacharyya RP, Mina MJ, et al. Cross-sectional assessment of SARS-CoV-2 viral load by symptom status in Massachusetts congregate living facilities. J Infect Dis. 2021. doi:10.1093/infdis/jiab367

Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.

Neggers JE, Paolella BR, Asfaw A, et al. Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q. Cell Rep. 2021;36(2):109367. doi:10.1016/j.celrep.2021.109367