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Publications

Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation.

Heckel E, Cagnone G, Agnihotri T, et al. Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation. JCI insight. 2022;7(6). doi:10.1172/jci.insight.154174

Insulin Prevents Hypercholesterolemia by Suppressing 12α-Hydroxylated Bile Acids.

Semova I, Levenson AE, Krawczyk J, et al. Insulin Prevents Hypercholesterolemia by Suppressing 12α-Hydroxylated Bile Acids. Circulation. 2022;145(13):969-982. doi:10.1161/CIRCULATIONAHA.120.045373

Dietary lignans, plasma enterolactone levels, and metabolic risk in men: exploring the role of the gut microbiome.

Li Y, Wang F, Li J, et al. Dietary lignans, plasma enterolactone levels, and metabolic risk in men: exploring the role of the gut microbiome. BMC microbiology. 2022;22(1):82. doi:10.1186/s12866-022-02495-0

Decoding the diversity of killer immunoglobulin-like receptors by deep sequencing and a high-resolution imputation method.

Sakaue S, Hosomichi K, Hirata J, et al. Decoding the diversity of killer immunoglobulin-like receptors by deep sequencing and a high-resolution imputation method. Cell genomics. 2022;2(3):100101. doi:10.1016/j.xgen.2022.100101

Characterization of intrinsically disordered regions in proteins informed by human genetic diversity.

Ahmed SS, Rifat ZT, Lohia R, et al. Characterization of intrinsically disordered regions in proteins informed by human genetic diversity. PLoS Comput Biol. 2022;18(3):e1009911. doi:10.1371/journal.pcbi.1009911

BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes.

Schaefer EJ, Wang HC, Karp HQ, et al. BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes. Blood Cancer Discov. 2022;3(2):116-135. doi:10.1158/2643-3230.BCD-21-0115

Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease.

Fahed AC, Wang M, Patel AP, et al. Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease. JAMA Netw Open. 2022;5(3):e222687. doi:10.1001/jamanetworkopen.2022.2687

Deep learning-enabled assessment of cardiac allograft rejection from endomyocardial biopsies.

Lipkova J, Chen TY, Lu MY, et al. Deep learning-enabled assessment of cardiac allograft rejection from endomyocardial biopsies. Nat Med. 2022;28(3):575-582. doi:10.1038/s41591-022-01709-2

Establishing the role of the gut microbiota in susceptibility to recurrent urinary tract infections.

Worby CJ, Olson BS, Dodson KW, Earl AM, Hultgren SJ. Establishing the role of the gut microbiota in susceptibility to recurrent urinary tract infections. J Clin Invest. 2022;132(5). doi:10.1172/JCI158497

Total synthesis of himastatin.

D’Angelo KA, Schissel CK, Pentelute BL, Movassaghi M. Total synthesis of himastatin. Science. 2022;375(6583):894-899. doi:10.1126/science.abm6509