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Publications

Genomics reveals eleven obesity endotypes with distinct biological and phenotypic signatures.

Kim MS, Song M, Kim H, et al. Genomics reveals eleven obesity endotypes with distinct biological and phenotypic signatures. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.06.30.25330607

PROFET Predicts Continuous Gene Expression Dynamics from scRNA-seq Data to Elucidate Heterogeneity of Cancer Treatment Responses.

Cheng YC, Gu H, McDonald TO, et al. PROFET Predicts Continuous Gene Expression Dynamics from scRNA-seq Data to Elucidate Heterogeneity of Cancer Treatment Responses. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.06.27.662030

Sideroflexins enable mitochondrial transport of polar neutral amino acids.

Block S, Chi F, Rosen PC, et al. Sideroflexins enable mitochondrial transport of polar neutral amino acids. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.06.18.660357

Polyamines buffer labile iron to suppress ferroptosis.

Sharma P, Keys HR, Müller S, et al. Polyamines buffer labile iron to suppress ferroptosis. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.06.30.662349

MORPH Predicts the Single-Cell Outcome of Genetic Perturbations Across Conditions and Data Modalities.

He C, Zhang J, Dahleh M, Uhler C. MORPH Predicts the Single-Cell Outcome of Genetic Perturbations Across Conditions and Data Modalities. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.06.27.661992

MarkerMatch: A Proximity-Based Probe-Matching Algorithm for Joint Analysis of Copy-Number Variants from Different Genotyping Arrays.

Ivankovic F, Yu D, Shen J, et al. MarkerMatch: A Proximity-Based Probe-Matching Algorithm for Joint Analysis of Copy-Number Variants from Different Genotyping Arrays. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.06.30.662249

spRefine Denoises and Imputes Spatial Transcriptomics with a Reference-Free Framework Powered by Genomic Language Model.

Liu T, Huang T, Jin W, Chu T, Ying R, Zhao H. spRefine Denoises and Imputes Spatial Transcriptomics with a Reference-Free Framework Powered by Genomic Language Model. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.04.22.649977

Genome-wide extraction of differentially methylated DNA regions using adapter-anchored proximity primers.

Darbeheshti F, Zeggar HR, Salmani H, et al. Genome-wide extraction of differentially methylated DNA regions using adapter-anchored proximity primers. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.06.29.660377

When Close Is Not Close Enough: Cardiomyopathy After Deep Septal Pacing.

Shaik A, Frankel DS, Khurshid S. When Close Is Not Close Enough: Cardiomyopathy After Deep Septal Pacing. Journal of cardiovascular electrophysiology. 2025;36(8):1996-1998. doi:10.1111/jce.16796

AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions.

Gear R, Kalitsis P, Glass M, et al. AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions. American journal of medical genetics. Part A. 2025:e64153. doi:10.1002/ajmg.a.64153