Publications

Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities.

Chami N, Wang Z, Svenstrup V, et al. Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities. Nature medicine. 2025. doi:10.1038/s41591-025-03931-0

Applying weighted Cox regression to genome-wide association studies of time-to-event phenotypes.

Li Y, Ma Y, Xu H, et al. Applying weighted Cox regression to genome-wide association studies of time-to-event phenotypes. Nature computational science. 2025. doi:10.1038/s43588-025-00864-z

CF10 Displayed Improved Activity Relative to 5-FU in a Mouse CRLM Model Under Conditions of Physiological Folate.

Okechukwu CC, Ma X, Li W, et al. CF10 Displayed Improved Activity Relative to 5-FU in a Mouse CRLM Model Under Conditions of Physiological Folate. Cancers. 2025;17(17). doi:10.3390/cancers17172739

Pathway-specific polygenic scores substantially increase the discovery of gene-adiposity interactions impacting liver biomarkers.

Westerman KE, Chasman DI, Gauderman J, Durvasula A. Pathway-specific polygenic scores substantially increase the discovery of gene-adiposity interactions impacting liver biomarkers. HGG advances. 2025;7(1):100515. doi:10.1016/j.xhgg.2025.100515

Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation.

Liao G, Nakayama T, Zhu B, et al. Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation. Immunity. 2025. doi:10.1016/j.immuni.2025.08.009

Towards modeling evolving longitudinal health trajectories with a transformer-based deep learning model.

Moen H, Raj V, Vabalas A, et al. Towards modeling evolving longitudinal health trajectories with a transformer-based deep learning model. Annals of epidemiology. 2025;111:30-43. doi:10.1016/j.annepidem.2025.08.025

Regenerate to "Rejuvenate": Insights From Adult Resident Stem Cells of Aged Flatworms and Mice.

Murach KA, Dungan CM, Chambers TL, et al. Regenerate to "Rejuvenate": Insights From Adult Resident Stem Cells of Aged Flatworms and Mice. Aging cell. 2025:e70236. doi:10.1111/acel.70236

An Inflammatory and Quiescent HSC Subpopulation Expands with Age in Humans.

Safina KR, Kotliar DA, Curtis M, et al. An Inflammatory and Quiescent HSC Subpopulation Expands with Age in Humans. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.01.673389

Blended Length Genome Sequencing (blend-seq): Combining Short Reads with Low-Coverage Long Reads to Maximize Variant Discovery.

Magner R, Cunial F, Basu S, et al. Blended Length Genome Sequencing (blend-seq): Combining Short Reads with Low-Coverage Long Reads to Maximize Variant Discovery. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2024.11.01.621515

Structural basis for the function of long noncoding RNA in neural stem cells.

Saha P, Patel S, Tavares RC, et al. Structural basis for the function of long noncoding RNA in neural stem cells. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.01.671568

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Publications

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