Litichevskiy L, Peckner R, Abelin JG, et al. A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations. Cell Syst. 2018;6(4):424-443.e7. doi:10.1016/j.cels.2018.03.012
Proteomics Platform
Khajuria RK, Munschauer M, Ulirsch JC, et al. Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis. Cell. 2018;173(1):90-103.e19. doi:10.1016/j.cell.2018.02.036
Mohanan V, Nakata T, Desch N, et al. is a colitis risk gene that regulates stability of epithelial adherens junctions. Science. 2018;359(6380):1161-1166. doi:10.1126/science.aan0814
Cheng Z, Otto GM, Powers EN, et al. Pervasive, Coordinated Protein-Level Changes Driven by Transcript Isoform Switching during Meiosis. Cell. 2018;172(5):910-923.e16. doi:10.1016/j.cell.2018.01.035
Mundt F, Rajput S, Li S, et al. Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancers. Cancer Res. 2018. doi:10.1158/0008-5472.CAN-17-1990
Horwitz SM, Koch R, Porcu P, et al. Activity of the PI3K-δ,γ inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphoma. Blood. 2018;131(8):888-898. doi:10.1182/blood-2017-08-802470
Keenan AB, Jenkins SL, Jagodnik KM, et al. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. Cell Syst. 2018;6(1):13-24. doi:10.1016/j.cels.2017.11.001
Bark SKN, Ahmad R, Dantzler K, et al. Quantitative Proteomic Profiling Reveals Novel Surface Antigens and Possible Vaccine Candidates. Mol Cell Proteomics. 2018;17(1):43-60. doi:10.1074/mcp.RA117.000076
Tripathi BK, Grant T, Qian X, et al. Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1. J Cell Biol. 2017;216(12):4255-4270. doi:10.1083/jcb.201703105
Udeshi ND, Pedram K, Svinkina T, et al. Antibodies to biotin enable large-scale detection of biotinylation sites on proteins. Nat Methods. 2017;14(12):1167-1170. doi:10.1038/nmeth.4465