Steinebach C, Lindner S, Udeshi ND, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018;13(9):2771-2782. doi:10.1021/acschembio.8b00693
Proteomics Platform
Kahn JD, Miller PG, Silver AJ, et al. -truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells. Blood. 2018;132(11):1095-1105. doi:10.1182/blood-2018-05-850339
Archer TC, Ehrenberger T, Mundt F, et al. Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups. Cancer Cell. 2018;34(3):396-410.e8. doi:10.1016/j.ccell.2018.08.004
Munschauer M, Nguyen CT, Sirokman K, et al. The NORAD lncRNA assembles a topoisomerase complex critical for genome stability. Nature. 2018;561(7721):132-136. doi:10.1038/s41586-018-0453-z
Wang YJ, Vaidyanathan PP, Rojas-Duran MF, et al. Lso2 is a conserved ribosome-bound protein required for translational recovery in yeast. PLoS Biol. 2018;16(9):e2005903. doi:10.1371/journal.pbio.2005903
Jin YN, Schlueter PJ, Jurisch-Yaksi N, et al. Noncanonical translation via deadenylated 3’ UTRs maintains primordial germ cells. Nat Chem Biol. 2018;14(9):844-852. doi:10.1038/s41589-018-0098-0
Sandoval GJ, Pulice JL, Pakula H, et al. Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis. Mol Cell. 2018;71(4):554-566.e7. doi:10.1016/j.molcel.2018.06.040
Gopal S, Lu Q, Man JJ, et al. A phosphoproteomic signature in endothelial cells predicts vascular toxicity of tyrosine kinase inhibitors used in CML. Blood Adv. 2018;2(14):1680-1684. doi:10.1182/bloodadvances.2018020396
Graham DB, Jasso GJ, Mok A, et al. Nitric Oxide Engages an Anti-inflammatory Feedback Loop Mediated by Peroxiredoxin 5 in Phagocytes. Cell Rep. 2018;24(4):838-850. doi:10.1016/j.celrep.2018.06.081
Zhang Y, Burberry A, Wang JY, et al. The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis. Genes Dev. 2018;32(13-14):929-943. doi:10.1101/gad.313932.118