The Human Cell Atlas. 1.Regev A, Teichmann SA, Lander ES, et al. The Human Cell Atlas. Elife. 2017;6. doi:10.7554/eLife.27041. Read more
Efficient Generation of Transcriptomic Profiles by Random Composite Measurements. 1.Cleary B, Cong L, Cheung A, Lander ES, Regev A. Efficient Generation of Transcriptomic Profiles by Random Composite Measurements. Cell. 2017;171(6):1424-1436.e18. doi:10.1016/j.cell.2017.10.023. Read more
A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients. 1.Hall AB, Yassour M, Sauk J, et al. A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients. Genome Med. 2017;9(1):103. doi:10.1186/s13073-017-0490-5. Read more
RNA targeting with CRISPR-Cas13. 1.Abudayyeh OO, Gootenberg JS, Essletzbichler P, et al. RNA targeting with CRISPR-Cas13. Nature. 2017;550(7675):280-284. doi:10.1038/nature24049. Read more
Cohesin Loss Eliminates All Loop Domains. 1.Rao SSP, Huang S-C, St Hilaire BG, et al. Cohesin Loss Eliminates All Loop Domains. Cell. 2017;171(2):305-320.e24. doi:10.1016/j.cell.2017.09.026. Read more
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. 1.Polak P, Kim J, Braunstein LZ, et al. A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. Nat Genet. 2017;49(10):1476-1486. doi:10.1038/ng.3934. Read more
Rare germline variants in ATM are associated with chronic lymphocytic leukemia. 1.Tiao G, Improgo MR, Kasar S, et al. Rare germline variants in ATM are associated with chronic lymphocytic leukemia. Leukemia. 2017;31(10):2244-2247. doi:10.1038/leu.2017.201. Read more
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. 1.Joung J, Engreitz JM, Konermann S, et al. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. Nature. 2017;548(7667):343-346. doi:10.1038/nature23451. Read more
An immunogenic personal neoantigen vaccine for patients with melanoma. 1.Ott PA, Hu Z, Keskin DB, et al. An immunogenic personal neoantigen vaccine for patients with melanoma. Nature. 2017;547(7662):217-221. doi:10.1038/nature22991. Read more
Recurrent and functional regulatory mutations in breast cancer. 1.Rheinbay E, Parasuraman P, Grimsby J, et al. Recurrent and functional regulatory mutations in breast cancer. Nature. 2017;547(7661):55-60. doi:10.1038/nature22992. Read more