Development and Validation of a Mass Spectrometry-Based Assay for the Molecular Diagnosis of Mucin-1 Kidney Disease. 1.Blumenstiel B, DeFelice M, Birsoy O, et al. Development and Validation of a Mass Spectrometry-Based Assay for the Molecular Diagnosis of Mucin-1 Kidney Disease. J Mol Diagn. 2016;18(4):566-71. doi:10.1016/j.jmoldx.2016.03.003. Read more
Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom. 1.Durand NC, Robinson JT, Shamim MS, et al. Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom. Cell Syst. 2016;3(1):99-101. doi:10.1016/j.cels.2015.07.012. Read more
Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability. 1.Yassour M, Vatanen T, Siljander H, et al. Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability. Sci Transl Med. 2016;8(343):343ra81. doi:10.1126/scitranslmed.aad0917. Read more
Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. 1.Khera AV, Won H-H, Peloso GM, et al. Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. J Am Coll Cardiol. 2016;67(22):2578-89. doi:10.1016/j.jacc.2016.03.520. Read more
Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay. 1.Tewhey R, Kotliar D, Park DS, et al. Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay. Cell. 2016;165(6):1519-29. doi:10.1016/j.cell.2016.04.027. Read more
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition. 1.Burger JA, Landau DA, Taylor-Weiner A, et al. Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition. Nat Commun. 2016;7:11589. doi:10.1038/ncomms11589. Read more
Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. 1.Giannakis M, Mu XJ, Shukla SA, et al. Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Rep. 2016. doi:10.1016/j.celrep.2016.03.075. Read more
Single Guide RNA Library Design and Construction. 1.Wang T, Lander ES, Sabatini DM. Single Guide RNA Library Design and Construction. Cold Spring Harb Protoc. 2016;2016(3):pdb.prot090803. doi:10.1101/pdb.prot090803. Read more
Viral Packaging and Cell Culture for CRISPR-Based Screens. 1.Wang T, Lander ES, Sabatini DM. Viral Packaging and Cell Culture for CRISPR-Based Screens. Cold Spring Harb Protoc. 2016;2016(3):pdb.prot090811. doi:10.1101/pdb.prot090811. Read more
Large-Scale Single Guide RNA Library Construction and Use for CRISPR-Cas9-Based Genetic Screens. 1.Wang T, Lander ES, Sabatini DM. Large-Scale Single Guide RNA Library Construction and Use for CRISPR-Cas9-Based Genetic Screens. Cold Spring Harb Protoc. 2016;2016(3):pdb.top086892. doi:10.1101/pdb.top086892. Read more