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Publications

Modeling suggests SARS-CoV-2 rebound after nirmatrelvir-ritonavir treatment is driven by target cell preservation coupled with incomplete viral clearance.

Phan T, Ribeiro RM, Edelstein GE, et al. Modeling suggests SARS-CoV-2 rebound after nirmatrelvir-ritonavir treatment is driven by target cell preservation coupled with incomplete viral clearance. Journal of virology. 2025:e0162324. doi:10.1128/jvi.01623-24

Multi-locus CRISPRi targeting with a single truncated guide RNA.

Moore MM, Wekhande S, Issner R, et al. Multi-locus CRISPRi targeting with a single truncated guide RNA. Nature communications. 2025;16(1):1357. doi:10.1038/s41467-025-56144-x

Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease.

Schunkert H, Di Angelantonio E, Inouye M, et al. Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease. European heart journal. 2025. doi:10.1093/eurheartj/ehae649

Genetically Predicted IL-18 Inhibition and Risk of Cardiovascular Events: A Mendelian Randomization Study.

Brennan SO, Kelly PJ, Gorey S, et al. Genetically Predicted IL-18 Inhibition and Risk of Cardiovascular Events: A Mendelian Randomization Study. Circulation. 2025;151(5):334-336. doi:10.1161/CIRCULATIONAHA.124.072238

Introducing the Global Alliance for Spatial Technologies (GESTALT).

Plummer JT, Vlachos IS, Martelotto LG. Introducing the Global Alliance for Spatial Technologies (GESTALT). Nature genetics. 2025. doi:10.1038/s41588-024-02066-1

Ultrasound-Guided Nerve Hydrodissection for the Management of Carpal Tunnel Syndrome: A Systematic Review and Network Meta-Analysis.

Lee K, Park JM, Yoon SY, et al. Ultrasound-Guided Nerve Hydrodissection for the Management of Carpal Tunnel Syndrome: A Systematic Review and Network Meta-Analysis. Yonsei medical journal. 2025;66(2):111-120. doi:10.3349/ymj.2024.0089

Deep learning to decode sites of RNA translation in normal and cancerous tissues.

Clauwaert J, McVey Z, Gupta R, et al. Deep learning to decode sites of RNA translation in normal and cancerous tissues. Nature communications. 2025;16(1):1275. doi:10.1038/s41467-025-56543-0

Global outcomes and prognosis for relapsed/refractory mature T-cell and NK-cell lymphomas: results from the PETAL consortium.

Han JX, Koh MJ, Boussi L, et al. Global outcomes and prognosis for relapsed/refractory mature T-cell and NK-cell lymphomas: results from the PETAL consortium. Blood advances. 2025;9(3):583-602. doi:10.1182/bloodadvances.2024014674

Longitudinal Evaluation of Genetic Hypertrophic Cardiomyopathy Penetrance and Transition to Disease in an Academic Biobank.

Shin JY, Small AM, Zawatsky CLB, et al. Longitudinal Evaluation of Genetic Hypertrophic Cardiomyopathy Penetrance and Transition to Disease in an Academic Biobank. JACC. Advances. 2025;4(2):101520. doi:10.1016/j.jacadv.2024.101520

Genetic Predisposition to Coronary Artery Disease: Evaluating Statin Therapy in Elder Populations From PROSPER.

Choi SH, Young R, Koyama S, et al. Genetic Predisposition to Coronary Artery Disease: Evaluating Statin Therapy in Elder Populations From PROSPER. JACC. Advances. 2025;4(2):101535. doi:10.1016/j.jacadv.2024.101535