Publications

Correcting a pathogenic mitochondrial DNA mutation by base editing in mice.

Barrera-Paez JD, Bacman SR, Balla T, et al. Correcting a pathogenic mitochondrial DNA mutation by base editing in mice. Science translational medicine. 2025;17(783):eadr0792. doi:10.1126/scitranslmed.adr0792

Organ-specific microenvironments drive divergent T cell evolution in acute graft-versus-host disease.

Omdahl KI, Bermea RS, Fleming R, et al. Organ-specific microenvironments drive divergent T cell evolution in acute graft-versus-host disease. Science translational medicine. 2025;17(783):eads1298. doi:10.1126/scitranslmed.ads1298

Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multi-Ancestry Population Cohorts.

Luckett AM, Oram RA, Deutsch AJ, et al. Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multi-Ancestry Population Cohorts. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.01.16.25320691

Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease.

Castanho I, Yeganeh PN, Boix CA, et al. Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer’s disease. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.01.13.632801

Combined PARP14 inhibition and PD-1 blockade promotes cytotoxic T cell quiescence and modulates macrophage polarization in relapsed melanoma.

Leshem R, Sefton KN, Wong CW, et al. Combined PARP14 inhibition and PD-1 blockade promotes cytotoxic T cell quiescence and modulates macrophage polarization in relapsed melanoma. Journal for immunotherapy of cancer. 2025;13(1). doi:10.1136/jitc-2024-010683

Integrating representation learning, permutation, and optimization to detect lineage-related gene expression patterns.

Schlüter HM, Uhler C. Integrating representation learning, permutation, and optimization to detect lineage-related gene expression patterns. Nature communications. 2025;16(1):1062. doi:10.1038/s41467-025-56388-7

A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer.

Rendo V, Schubert M, Khuu N, et al. A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer. Nature communications. 2025;16(1):1077. doi:10.1038/s41467-025-56301-2

A genome-wide atlas of human cell morphology.

Ramezani M, Weisbart E, Bauman J, et al. A genome-wide atlas of human cell morphology. Nature methods. 2025. doi:10.1038/s41592-024-02537-7

Activated Cardiac Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production.

Little DT, Howard CM, Pendergraft E, et al. Activated Cardiac Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production. American journal of physiology. Cell physiology. 2025. doi:10.1152/ajpcell.00786.2024

The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis.

Marin-Rodero M, Cintado E, Walker AJ, et al. The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis. Science immunology. 2025:eadu2910. doi:10.1126/sciimmunol.adu2910

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Publications

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