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Publications

Are CRISPR Screens Providing the Next Generation of Therapeutic Targets?

Vazquez F, Sellers WR. Are CRISPR Screens Providing the Next Generation of Therapeutic Targets? Cancer Res. 2021;81(23):5806-5809. doi:10.1158/0008-5472.CAN-21-1784

Multiomic characterization of oncogenic signaling mediated by wild-type and mutant RIT1.

Lo A, Holmes K, Kamlapurkar S, et al. Multiomic characterization of oncogenic signaling mediated by wild-type and mutant RIT1. Sci Signal. 2021;14(711):eabc4520. doi:10.1126/scisignal.abc4520

Genomic Profiling of Lung Adenocarcinoma in Never-Smokers.

Devarakonda S, Li Y, Rodrigues FM, et al. Genomic Profiling of Lung Adenocarcinoma in Never-Smokers. J Clin Oncol. 2021;39(33):3747-3758. doi:10.1200/JCO.21.01691

Racial, Ethnic, and Socioeconomic Disparities in Curative Treatment Receipt and Survival in Hepatocellular Carcinoma.

Wagle NS, Park S, Washburn D, et al. Racial, Ethnic, and Socioeconomic Disparities in Curative Treatment Receipt and Survival in Hepatocellular Carcinoma. Hepatol Commun. 2021. doi:10.1002/hep4.1863

Diversity, multifaceted evolution, and facultative saprotrophism in the European Batrachochytrium salamandrivorans epidemic.

Kelly M, Pasmans F, Muñoz JF, et al. Diversity, multifaceted evolution, and facultative saprotrophism in the European Batrachochytrium salamandrivorans epidemic. Nat Commun. 2021;12(1):6688. doi:10.1038/s41467-021-27005-0

Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes.

Kong L, Moorlag SJCFM, Lefkovith A, et al. Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes. Cell Rep. 2021;37(7):110028. doi:10.1016/j.celrep.2021.110028

Electrocardiogram-based Deep Learning and Clinical Risk Factors to Predict Atrial Fibrillation.

Khurshid S, Friedman S, Reeder C, et al. Electrocardiogram-based Deep Learning and Clinical Risk Factors to Predict Atrial Fibrillation. Circulation. 2021. doi:10.1161/CIRCULATIONAHA.121.057480

Returning actionable genomic results in a research biobank: Analytic validity, clinical implementation, and resource utilization.

Zawatsky CLB, Shah N, Machini K, et al. Returning actionable genomic results in a research biobank: Analytic validity, clinical implementation, and resource utilization. Am J Hum Genet. 2021. doi:10.1016/j.ajhg.2021.10.005

Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram.

Biancalani T, Scalia G, Buffoni L, et al. Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram. Nat Methods. 2021;18(11):1352-1362. doi:10.1038/s41592-021-01264-7

Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin.

Wang JS, Kamath T, Mazur CM, et al. Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin. Nat Commun. 2021;12(1):6271. doi:10.1038/s41467-021-26571-7