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Imaging Platform
Wieder N, Fried J, Kim C, et al. FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Cell metabolism. 2023. doi:10.1016/j.cmet.2023.03.018
Haghighi M, Caicedo JC, Cimini BA, Carpenter AE, Singh S. High-dimensional gene expression and morphology profiles of cells across 28,000 genetic and chemical perturbations. Nat Methods. 2022. doi:10.1038/s41592-022-01667-0
Rohban MH, Fuller AM, Tan C, et al. Virtual screening for small-molecule pathway regulators by image-profile matching. Cell Syst. 2022. doi:10.1016/j.cels.2022.08.003
Filby A, Carpenter AE. A New Image for Cell Sorting. N Engl J Med. 2022;386(18):1755-1758. doi:10.1056/NEJMcibr2200971
Chow YL, Singh S, Carpenter AE, Way GP. Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic. PLoS Comput Biol. 2022;18(2):e1009888. doi:10.1371/journal.pcbi.1009888
Bagheri N, Carpenter AE, Lundberg E, Plant AL, Horwitz R. The new era of quantitative cell imaging-challenges and opportunities. Mol Cell. 2022;82(2):241-247. doi:10.1016/j.molcel.2021.12.024
Rees P, Summers HD, Filby A, Carpenter AE, Doan M. Imaging flow cytometry. Nature Reviews Methods Primers. 2022.
Jamali N, Dobson ET, Eliceiri KW, Carpenter AE, Cimini BA. 2020 BioImage Analysis Survey: Community experiences and needs for the future. Biol Imaging. 2022;1. doi:10.1017/S2633903X21000039
Way G, Natoli T, Adeboye A, et al. Morphology and gene expression profiling provide complementary information for mapping cell state. Cell systems. 2022;13(11):911-923.e9. doi:10.1016/j.cels.2022.10.001