Ó³»­´«Ã½

Chen PJ, Hussmann JA, Yan J, et al. Enhanced prime editing systems by manipulating cellular determinants of editing outcomes. Cell. 2021;184(22):5635-5652.e29. doi:10.1016/j.cell.2021.09.018

Clemons PA, Bittker JA, Wagner FF, et al. The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes. SLAS Discov. 2021;26(7):855-861. doi:10.1177/24725552211019410

Modell AE, Lai S, Nguyen TM, Choudhary A. Bifunctional modalities for repurposing protein function. Cell chemical biology. 2021;28(7):1081-1089. doi:10.1016/j.chembiol.2021.06.005

Kahraman S, Manna D, Dirice E, et al. Harnessing reaction-based probes to preferentially target pancreatic β-cells and β-like cells. Life science alliance. 2021;4(4). doi:10.26508/lsa.202000840

Modell AE, Siriwardena SU, Shoba VM, Li X, Choudhary A. Chemical and optical control of CRISPR-associated nucleases. Current opinion in chemical biology. 2021;60:113-121. doi:10.1016/j.cbpa.2020.10.003

Morrison MS, Wang T, Raguram A, Hemez C, Liu DR. Disulfide-compatible phage-assisted continuous evolution in the periplasmic space. Nature communications. 2021;12(1):5959. doi:10.1038/s41467-021-26279-8

Shen MW, Zhao KT, Liu DR. Reconstruction of evolving gene variants and fitness from short sequencing reads. Nature chemical biology. 2021;17(11):1188-1198. doi:10.1038/s41589-021-00876-6

Newby GA, Liu DR. In vivo somatic cell base editing and prime editing. Molecular therapy : the journal of the American Society of Gene Therapy. 2021;29(11):3107-3124. doi:10.1016/j.ymthe.2021.09.002

Krishnamurthy S, Traore S, Cooney AL, et al. Functional correction of CFTR mutations in human airway epithelial cells using adenine base editors. Nucleic acids research. 2021;49(18):10558-10572. doi:10.1093/nar/gkab788

Koblan LW, Arbab M, Shen MW, et al. Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning. Nature biotechnology. 2021;39(11):1414-1425. doi:10.1038/s41587-021-00938-z