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Publications

MASI enables fast model-free standardization and integration of single-cell transcriptomics data.

Xu Y, Kramann R, McCord RP, Hayat S. MASI enables fast model-free standardization and integration of single-cell transcriptomics data. Communications biology. 2023;6(1):465. doi:10.1038/s42003-023-04820-3

Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome.

Barry A, McNulty MT, Jia X, et al. Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome. Nature communications. 2023;14(1):2481. doi:10.1038/s41467-023-37985-w

Identifying shared genetic architecture between rheumatoid arthritis and other conditions: a phenome-wide association study with genetic risk scores.

Zhang HG, McDermott G, Seyok T, et al. Identifying shared genetic architecture between rheumatoid arthritis and other conditions: a phenome-wide association study with genetic risk scores. EBioMedicine. 2023;92:104581. doi:10.1016/j.ebiom.2023.104581

High-throughput approaches to uncover synergistic drug combinations in leukemia.

Chory EJ, Wang M, Ceribelli M, et al. High-throughput approaches to uncover synergistic drug combinations in leukemia. SLAS discovery : advancing life sciences R & D. 2023. doi:10.1016/j.slasd.2023.04.004

Molecular markers of metastatic disease in KRAS mutant lung adenocarcinoma.

Boiarsky D, Lydon CA, Chambers ES, et al. Molecular markers of metastatic disease in KRAS mutant lung adenocarcinoma. Annals of oncology : official journal of the European Society for Medical Oncology. 2023. doi:10.1016/j.annonc.2023.04.514

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.

Tanzo JT, Li VL, Wiggenhorn AL, et al. CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels. The Journal of biological chemistry. 2023:104764. doi:10.1016/j.jbc.2023.104764

SynapseCLR: Uncovering features of synapses in primary visual cortex through contrastive representation learning.

Wilson A, Babadi M. SynapseCLR: Uncovering features of synapses in primary visual cortex through contrastive representation learning. Patterns (New York, N.Y.). 2023;4(4):100693. doi:10.1016/j.patter.2023.100693

Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency.

Das A, Tabori U, Nahum LCS, et al. Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023. doi:10.1158/1078-0432.CCR-23-0411

Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy.

Khoshkhoo S, Wang Y, Chahine Y, et al. Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy. JAMA neurology. 2023. doi:10.1001/jamaneurol.2023.0473

The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.

Weinstock JS, Laurie CA, Broome JG, et al. The genetic determinants of recurrent somatic mutations in 43,693 blood genomes. Science advances. 2023;9(17):eabm4945. doi:10.1126/sciadv.abm4945