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Publications

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing.

Anzalone AV, Gao XD, Podracky CJ, et al. Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing. Nat Biotechnol. 2021. doi:10.1038/s41587-021-01133-w

Author Correction: Engineered pegRNAs improve prime editing efficiency.

Nelson JW, Randolph PB, Shen SP, et al. Author Correction: Engineered pegRNAs improve prime editing efficiency. Nat Biotechnol. 2021. doi:10.1038/s41587-021-01175-0

Age-related Diseases of Inflammation in Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia.

Weeks LD, Marinac CR, Redd RA, et al. Age-related Diseases of Inflammation in Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia. Blood. 2021. doi:10.1182/blood.2021014418

Mapping the human genetic architecture of COVID-19.

COVID-19 Host Genetics Initiative. Mapping the human genetic architecture of COVID-19. Nature. 2021;600(7889):472-477. doi:10.1038/s41586-021-03767-x

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

Ito T, Young MJ, Li R, et al. Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. Nat Genet. 2021;53(12):1664-1672. doi:10.1038/s41588-021-00967-z

Are CRISPR Screens Providing the Next Generation of Therapeutic Targets?

Vazquez F, Sellers WR. Are CRISPR Screens Providing the Next Generation of Therapeutic Targets? Cancer Res. 2021;81(23):5806-5809. doi:10.1158/0008-5472.CAN-21-1784

Multiomic characterization of oncogenic signaling mediated by wild-type and mutant RIT1.

Lo A, Holmes K, Kamlapurkar S, et al. Multiomic characterization of oncogenic signaling mediated by wild-type and mutant RIT1. Sci Signal. 2021;14(711):eabc4520. doi:10.1126/scisignal.abc4520

Genomic Profiling of Lung Adenocarcinoma in Never-Smokers.

Devarakonda S, Li Y, Rodrigues FM, et al. Genomic Profiling of Lung Adenocarcinoma in Never-Smokers. J Clin Oncol. 2021;39(33):3747-3758. doi:10.1200/JCO.21.01691

Racial, Ethnic, and Socioeconomic Disparities in Curative Treatment Receipt and Survival in Hepatocellular Carcinoma.

Wagle NS, Park S, Washburn D, et al. Racial, Ethnic, and Socioeconomic Disparities in Curative Treatment Receipt and Survival in Hepatocellular Carcinoma. Hepatol Commun. 2021. doi:10.1002/hep4.1863

Diversity, multifaceted evolution, and facultative saprotrophism in the European Batrachochytrium salamandrivorans epidemic.

Kelly M, Pasmans F, Muñoz JF, et al. Diversity, multifaceted evolution, and facultative saprotrophism in the European Batrachochytrium salamandrivorans epidemic. Nat Commun. 2021;12(1):6688. doi:10.1038/s41467-021-27005-0