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Publications

The challenges in treating Embryonal Tumors with Multilayered Rosettes (ETMR) and other infant brain tumors.

Bandopadhayay P, Chi SN. The challenges in treating Embryonal Tumors with Multilayered Rosettes (ETMR) and other infant brain tumors. Neuro Oncol. 2021. doi:10.1093/neuonc/noab206

Telomerase as a therapeutic target in glioblastoma.

Aquilanti E, Kageler L, Wen PY, Meyerson M. Telomerase as a therapeutic target in glioblastoma. Neuro Oncol. 2021. doi:10.1093/neuonc/noab203

Molecular basis for substrate recruitment to the PRMT5 methylosome.

Mulvaney KM, Blomquist C, Acharya N, et al. Molecular basis for substrate recruitment to the PRMT5 methylosome. Mol Cell. 2021;81(17):3481-3495.e7. doi:10.1016/j.molcel.2021.07.019

is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing.

Beauchamp EM, Leventhal M, Bernard E, et al. is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discov. 2021;2(5):500-517. doi:10.1158/2643-3230.BCD-20-0224

Genes in human obesity loci are causal obesity genes in C. elegans.

Ke W, Reed JN, Yang C, et al. Genes in human obesity loci are causal obesity genes in C. elegans. PLoS Genet. 2021;17(9):e1009736. doi:10.1371/journal.pgen.1009736

A highly multiplexed quantitative phosphosite assay for biology and preclinical studies.

Keshishian H, McDonald R, Mundt F, et al. A highly multiplexed quantitative phosphosite assay for biology and preclinical studies. Mol Syst Biol. 2021;17(9):e10156. doi:10.15252/msb.202010156

60 Years Young: The Evolving Role of Allogeneic Hematopoietic Stem Cell Transplantation in Cancer Immunotherapy.

Cieri N, Maurer K, Wu CJ. 60 Years Young: The Evolving Role of Allogeneic Hematopoietic Stem Cell Transplantation in Cancer Immunotherapy. Cancer Res. 2021;81(17):4373-4384. doi:10.1158/0008-5472.CAN-21-0301

Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning.

Wills JW, Verma JR, Rees BJ, et al. Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning. Arch Toxicol. 2021;95(9):3101-3115. doi:10.1007/s00204-021-03113-0

Population sequencing data reveal a compendium of mutational processes in the human germ line.

Seplyarskiy VB, Soldatov RA, Koch E, et al. Population sequencing data reveal a compendium of mutational processes in the human germ line. Science. 2021;373(6558):1030-1035. doi:10.1126/science.aba7408

Global phylogenomic analyses of Mycobacterium abscessus provide context for non cystic fibrosis infections and the evolution of antibiotic resistance.

Bronson RA, Gupta C, Manson AL, et al. Global phylogenomic analyses of Mycobacterium abscessus provide context for non cystic fibrosis infections and the evolution of antibiotic resistance. Nat Commun. 2021;12(1):5145. doi:10.1038/s41467-021-25484-9